While the economic value of anything depends on sellers and buyers agreeing on that value as civil equals in the absence of force, modern government is about nothing if not tampering with civil equality. By endowing some in society with power to force others to sell cheaper than they would, and forcing others yet to buy at higher prices — even to buy in the first place — modern government makes valuable some things that are not, and devalues others that are. Thus if you are not among the favored guests at the table where officials make detailed lists of who is to receive what at whose expense, you are on the menu.
This is an administration that almost employs more Goldman Sachs officials in financial and regulatory positions than Goldman Sachs itself does.  One of the first acts of Interior Secretary Ken Salazar was to hire a BP executive to serve as a deputy administrator for land and minerals management.  And now they’ve just hired to implement the new healthcare law someone who was just recently in charge of the lobbying and government activities of the nation’s largest private insurer.
If someone genuinely opposed big business, he would opposed all government regulation and all taxes.